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Allele : Mirc53<tm1.2Oshea> microRNA cluster 53, including Mir221 and Mir222; targeted mutation 1.2, John O'Shea
Primary Identifier  MGI:7327298 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mirc53
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted approximately 400 bp upstream from the start of Mir222 pre-miRNA. A neomycin cassette, second loxP site, and IRES-eGFP were inserted approximately 200 bp downstream from the end of Mir221 pre-miRNA. The neo cassette was excised via flpe-mediated recombination. Cre-mediated recombination deleted Mir221 and Mir222.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • Mirc53<->,
  • Mir221Mir222 KO,
  • Mirc53<->,
  • Mir221Mir222 KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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