| Primary Identifier | MGI:7328429 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Arhgap11a |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology replaced the last 55 nucleotides of the mouse Arhgap11a exon 5 starting at the position where in human ARHGAP11B, the C to G point mutation generates a new splice-donor site, with 141 nucleotides encoding the human ARHGAP11B-specific 47 amino acid sequence followed by three further nucleotides (TAG) to generate a translational stop codon. |
