Primary Identifier | MGI:7335171 | Allele Type | Targeted |
Attribute String | Null/knockout, Recombinase | Gene | Islr |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The CreERT2 cassette replaced the exon 2 of the Islr (Meflin) gene which encode the entire ORF. The Flippase Recognition Target (FRT)-flanked PGK-neo resistance gene was also inserted. Chimeras were mated with Rosa26-FLP mice to remove the neo-cassette. |