Primary Identifier | MGI:7335152 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Dino |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct introduced upstream of the lncRNA a loxP site and FRT site upstream of the lncRNA and an additional loxP site toward the 3 prime end of the lncRNA. The endogenous Trp53 response element within the Cdkn1a promoter remains intact. Expression was almost completely abrogated. |