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Allele : Cenpa<em1Ligu> centromere protein A; endonuclease-mediated mutation 1, Guohong Li

Primary Identifier  MGI:7336233 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Cenpa
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  Serine codon 62 (AGC) in exon 2 was changed to alanine (p.S62A) using an sgRNA (targeting GGAACTTACAACCATGCTGA) and an ssODN template with CRISPR/Cas9 technology. This mutation is the equivalent of the human p.S68A mutation and prevents phosphorylation of the residue.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • CENP-A S62A,
  • CENP-A S62A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories