Primary Identifier | MGI:7338923 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Cyfip2 |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
Project Collection | EUCOMM |
molecularNote | The L1L2_Bact_P cassette was inserted at position 46170548 of Chromosome 11 upstream of exon 6 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 6 at position 46171429. Exon 6 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying the Cyfip2tm1a(EUCOMM)Wtsi allele. |