| Primary Identifier | MGI:7339168 | Allele Type | Endonuclease-mediated |
| Attribute String | Modified regulatory region | Gene | Rr270 |
| Strain of Origin | CD-1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The conserved region, upstream of transcription start site 1 (TSS1) in the 5' UTR of Sox17 exon 1, was targeted with crRNAs (targeting TTTCTTCACTAAATGGGTGTTGG and ACTAGAGATTTACTGGGGTGGGG), tracrRNA and an ssODN template (GATACTTTGGGAGGAGTGTTGGGGCCAACCGCACTTCAGACCCGCCAGCAGTGTGAGTGGGCCATATTTCAGTTTCTTCACTAAATGGTGGGGTGGGGGTGGGTATCTGGACTAGAAGCCTGGCACGCCTGTCTGCTGTAGTCCGCAGCGGTATCACACTCAAACAGTGCAGGATTTCTA) using CRISPR/Cas9 technology, leading to a 117 bp deletion. |
