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Allele : Cyfip2<em1Bcgen> cytoplasmic FMR1 interacting protein 2; endonuclease-mediated mutation 1, Biocytogen LLC

Primary Identifier  MGI:7482711 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Cyfip2
Is Recombinase  false Is Wild Type  false
molecularNote  Arginine codon 87 (CGC) was changed to cysteine (TGC) (c.259C>T p.R87C) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the human p.Arg87Cys mutation associated with West syndrome.
  • mutations:
  • Single point mutation
  • synonyms:
  • Cyfip2<R87C>,
  • Cyfip2<R87C>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories