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Allele : Cdkn1c<tm1Abes> cyclin dependent kinase inhibitor 1C; targeted mutation 1, Arnaud Besson

Primary Identifier  MGI:7484339 Allele Type  Targeted
Gene  Cdkn1c Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Four mutations, arginine to alanine at residue 33 (p.R33A) and phenylalanine to aspartate at residue 36 (p.F36D) in the cyclin binding domain, and tryptophan to alanine at residue 63 (p.W63A) and phenylalanine to aspartate substitution at residue 67 (p.K67D) in the CDK binding domain were introduced into exon 2. A loxP-flanked neomycin selection cassette was inserted downstream of exon 4.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • p57<CK->,
  • p57<CK->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories