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Allele : Gas1<em1(icre/ERT2)Nono> growth arrest specific 1; endonuclease-mediated mutation 1, Noriaki Ono

Primary Identifier	MGI:7484373	Allele Type	Endonuclease-mediated
Attribute String	Inducible, Recombinase	Gene	Gas1
Strain of Origin	(C57BL/6J x SJL/J)F1	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

using CRISPR/Cas9 endonuclease-mediated genome editing, P2A-iCreERT2-bGH polyA sequences were inserted into the 3' UTR region of the growth arrest specific 1 (Gas1) gene on chromosome 13.

mutations:
Insertion

synonyms:
Gas1-creER,
Gas1-creER

earliestPublication:
Matsushita Y, et al. (2023) Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis. Nat Commun 14(1):2383

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

2 Publication categories

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