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Allele : Ehmt2<tm1.2Tara> euchromatic histone lysine N-methyltransferase 2; targeted mutation 1.2, Alexander Tarakhovsky
Primary Identifier  MGI:7380445 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ehmt2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 23 and 24 were floxed and an FRT-flanked neo cassette inserted into intron 24 via homologous recombination. The selection cassette was then removed by flp mediated recombination. Cre-mediated recombination resulted in out-of-frame splicing and nonsense mediated decay of the mutant transcript.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories





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