Primary Identifier | MGI:7356641 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr296 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The Mecp2 silencer 31 kb upstream of the gene was targeted with sgRNAs (targeting AAAAGGATATGGGATACTAG and GGTCCCCAATAGGGTCACCA) using CRISPR/Cas9 technology, resulting in a 1440 bp deletion. |