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Allele : Rr277<em1Flc> regulatory region 277; endonuclease-mediated mutation 1, Frank Conlon

Primary Identifier  MGI:7341596 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr277
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  This NKX2-5/CHD4-binding site-containing 488 bp cis-regulatory element (CRE) in the Acta1 3' UTR, suppressing Acta1 expression, was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in the deletion of the CRE.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Acta1<delta3'>,
  • Acta1<delta3'>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories