Primary Identifier | MGI:7341596 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr277 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This NKX2-5/CHD4-binding site-containing 488 bp cis-regulatory element (CRE) in the Acta1 3' UTR, suppressing Acta1 expression, was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in the deletion of the CRE. |