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Allele : Rr275<em1Mad> regulatory region 275; endonuclease-mediated mutation 1, Michael A Dyer

Primary Identifier  MGI:7341365 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr275
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  This Vsx2 enhancer was targeted with sgRNAs (UGGUGAUGGAGCGCAUAGCG and GGGCAGUGCAUCCCCUGUGG) and an ssODN template (CCAGCCACTGTCCCAGCCCGGGCTCTAAGTCTGACCCAAGCCGAAGTGCCTGCGCCCCGCTGGTGGGTGGGTGTGGACATCTTCCAGGCCCCAGGACACACCAGGAATCAAGAGGGAGGT) using CRISPR/Cas9 technology, resulting in a 4,045 bp deletion (chr12:84592972-84597016 GRCm39).
  • mutations:
  • Intergenic deletion
  • synonyms:
  • R2-22 delta,
  • R2-22 delta
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories