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Allele : Kif11<tm1.2Nat> kinesin family member 11; targeted mutation 1.2, Jeremy Nathans

Primary Identifier  MGI:7341372 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kif11
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were introduced to introns 4 and 6. An FRT-flanked neomycin cassette was inserted adjacent to the 5' loxP site. Exons 5 and 6 were removed via cre-mediated recombination. The neomycin cassette is present. Deletion of exons 5 and 6 leads to a 311 bp deletion resulting in a frameshift starting at codon 129 of the 1052 codon open reading frame.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories