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Allele : Rr291<tm2.1Mekk> regulatory region 291; targeted mutation 2.1, Marc Ekker
Primary Identifier  MGI:7356589 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr291
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  The intergenic Dlx5/Dlx6 forebrain enhancer was mutated (T/A>C/G) and a loxP site flanked neomycin resistance gene cassette was inserted downstream. The neo cassette was removed through subsequent cre-mediated recombination. The mutated nucleotide is ultraconserved, a polymorphism of which is associated with autism in humans.
  • mutations:
  • Insertion
  • synonyms:
  • vI56i,
  • vI56i
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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