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Allele : Tg(Rr596*-GH1)12Mrub transgene insertion 12, Marcelo Rubinstein
Primary Identifier  MGI:7341863 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Rr596*-GH1)12Mrub
Strain of Origin  either: (C57BL/6 x CBA)F2 or (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains the following elements: a neuron-specific enhancers-containing sequence 9-13 kb upstream of the Pomc gene transcription start site (with the two enhancers Rr279 (nPE1) and Rr280 (nPE2) deleted (585 bp, 172 bp)), the Herpes simplex virus TK gene minimal promoter and the human growth hormone gene gene. The transgene is expressed in neither hypothalamic arcuate neurons nor in pituitary melanotrophs and corticotrophs during embryonic development.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(GH1)12Mrub,
  • Tg(GH1)12Mrub
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories





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