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Allele : Del(4Nppb-Nppa)4Vmc deletion, Chr4, Vincent M Christoffels 4

Primary Identifier  MGI:7366921 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region, Null/knockout Gene  Del(4Nppb-Nppa)4Vmc
Strain of Origin  FVB/NRj Is Recombinase  false
Is Wild Type  false
molecularNote  The Nppa and Nppb genes were targeted with sgRNAs (targeting GACTACATGGCAGATCACCC and GGCCAGTTCAAACGATTTGT) using CRISPR/Cas9 technology, resulting in the deletion of both genes and enhancer Rr103616 in-between, as well as the 3' end of the Gm13054 lncRNA gene.
  • mutations:
  • Intergenic deletion,
  • Intragenic deletion
  • synonyms:
  • Nppa-Nppb<->,
  • Nppa-Nppb dKO,
  • Nppa-Nppb<->,
  • Nppa-Nppb dKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories