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Allele : Sepsecs<tm1.1Usch> Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; targeted mutation 1.1, Ulrich Schweizer
Primary Identifier  MGI:7367126 Allele Type  Targeted
Attribute String  Not Specified Gene  Sepsecs
Transmission  Germline Strain of Origin  (C57BL/6J x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct introduced the mutation responsible for the amino acid substitution of tyrosine to cysteine at position 334 (Y334C). Two silent mutations (p.I324 and p.T325) were also introduced. Flp-mediated recombination removed the FRT-flanked selection cassette.
  • mutations:
  • Insertion,
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories





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