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Allele : Rr316<em2Dilg> regulatory region 316; endonuclease-mediated mutation 2, Anna Dilger

Primary Identifier  MGI:7387088 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Rr316
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  TALEN-targeting using a homologous donor molecule created a G-to-A point mutation at chr7:142217981 (GRCm39) in the a multi-species conserved consensus sequence bound by a repressor, ZBED6, and created a silent A-to-G mutation at chr7:142217996 to disrupt one of the TALEN binding sites to prevent re-cleavage.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories