| Primary Identifier | MGI:7388568 | Allele Type | Targeted |
| Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence | Gene | Actb |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An IRES and loxP site flanked neomycin resistance gene and STOP cassette were inserted along with a constitutively active Kras cDNA with the amino acid substitution of glycine with aspartic acid at position 12 (p.G12D) into intron 1. Cre-mediated removal of the STOP cassette is required to achieve expression of the constitutively active Kras. |
