Primary Identifier | MGI:7387062 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Vav1-Mpl)EAmol |
Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene is generated using full length Mpl splice variant (SV) cDNA cloned into the HS321/45-vav vector, which contains the mouse genomic Vav1 promoter sequence. The Mpl splice variant has 7 amino acids deleted from the N-terminal domain. Founder line E carries an estimated single copy of the transgene and that the copy number is stable across multiple generations; however the transgene insertion site has not been confirmed. |