Primary Identifier | MGI:7398577 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Stat3 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Using CRISPR/CAS9 technology, a single nucleotide change was introduced into the Stat3 gene to create a knock-in mouse model harboring a de novo pathogenic human STAT3 variant (p.G421R). |