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Allele : Tg(Myh11-cre/ERT2)F31Gko transgene insertion F31, Gary K Owens

Primary Identifier  MGI:7398497 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Myh11-cre/ERT2)F31Gko
Strain of Origin  C57BL/6N Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  A bacterial artificial chromosome (BAC; RP23-151J22) containing the mouse smooth muscle myosin, heavy polypeptide 11 (Myh11) gene was used to insert a cre/ERT2 sequence (a mutated human estrogen receptor ligand binding domain fused to Cre) at the start codon of Myh11. The founder line F31, in which the transgene integrated into mouse Chromosome 2 in a region devoid of other genes [Chr2:178,826,578-178,826,802 (GRCm39)], was identified.
  • mutations:
  • Insertion
  • synonyms:
  • Myh11-CreER<T2>-RAD,
  • Myh11-CreER<T2>-RAD,
  • Myh11-CreER(T2)-RAD,
  • Myh11-CreER(T2)-RAD
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

4 Publication categories