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Allele : Ltbp4<em1(IMPC)Tcp> latent transforming growth factor beta binding protein 4; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7425804 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ltbp4
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ATCTCTGGACCGGTCCAAGC targeting the 5' side and AACCCGCGGTGTTGTCGCAG targeting the 3' side of a critical region (ENSMUSE00001403608, ENSMUSE00001398625, ENSMUSE00001395913 & ENSMUSE00001396773). This resulted in a 2,267-bp deletion of Chr7 from 27,024,452 to 27,026,718 (GRCm39).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories