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Allele : Elf4<em1Hdu> E74 like ETS transcription factor 4; endonuclease-mediated mutation 1, Hongqiang Du

Primary Identifier  MGI:7408147 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Elf4
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a TGG to CGC change resulting in a tryptophan to arginine substitution at amino acid 230 (W230R). This change corresponds to the W231R variant found in a pediatric patient with X-linked familial autoinflammatory syndrome.
  • mutations:
  • Nucleotide substitutions
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories