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Allele : Prr30<em1(IMPC)J> proline rich 30; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7408180 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Prr30
Inheritance Mode  Not Specified Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGTACTCAAGTGATAGCAGT and GAGCACCTGAAGCAGAATCC, which resulted in a 1970 bp deletion beginning at Chromosome 14 position 101,435,012 bp and ending after 101,436,981 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000364724 (exon 3) and 175 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to result in a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories