| Primary Identifier | MGI:7434711 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Lrch3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATATTGAACCAGTTTCCACT and TAGCTGGTGGAGCATTAGCC, which resulted in a 476 bp deletion beginning at Chromosome 16 position 32,950,234 bp and ending after 32,950,709 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001311437 (exon 2) and 331 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 87 and early truncation 16 amino acids later. |
