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Allele : Tnfrsf11a<tm1.1Sral> tumor necrosis factor receptor superfamily, member 11a, NFKB activator; targeted mutation 1.1, Stuart H Ralston
Primary Identifier  MGI:7427368 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Tnfrsf11a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was replaced with an exon 1 containing a 27 bp duplication (9 amino acid duplication of ALLLLCALL) in the signal peptide followed by a floxed neomycin cassette. The neomycin cassette was removed via flp-mediated recombination. This duplication has been identified in patients with early onset familial Paget’s disease of bone.
  • mutations:
  • Insertion
  • synonyms:
  • Tnfrsf11a<75dup27>,
  • Tnfrsf11a<75dup27>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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