| Help | About | Contact Us

Allele : Sik3<em9Iiis> SIK family kinase 3; endonuclease-mediated mutation 8, Masashi Yanagisawa and Hiromasa Funato

Primary Identifier	MGI:7412960	Allele Type	Endonuclease-mediated
Attribute String	Not Specified	Gene	Sik3
Strain of Origin	C57BL/6J-Sik3<Slp>	Is Recombinase	false
Is Wild Type	false

description	This allele was generated in zygotes containing Sik3^Slp.
molecularNote	CRISPR-targeting introduced the mutation responsible for the amino acid substitution threonine to alanine at position 221 (T221A).

mutations:
Single point mutation

synonyms:
Sik3<Slp;T221A>,
Sik3<Slp;T221A>

earliestPublication:
Kim SJ, et al. (2022) Kinase signalling in excitatory neurons regulates sleep quantity and depth. Nature 612(7940):512-518

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76814562

MouseMine