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Allele : Rr1367<em1Cya> regulatory region 1367; endonuclease-mediated mutation 1, Cyagen Biosciences

Primary Identifier	MGI:7413089	Allele Type	Endonuclease-mediated
Attribute String	Modified regulatory region	Gene	Rr1367
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

The cranial neural crest cell (CNCC) specific Sox9 enhancer (chr11:111459349-111460265 (GRCm39)) was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in a 1170 bp deletion that includes the enhancer.

mutations:
Intergenic deletion

synonyms:
Peak16<->,
Peak16<->

earliestPublication:
Chen Q, et al. (2022) Integration of 3D genome topology and local chromatin features uncovers enhancers underlying craniofacial-specific cartilage defects. Sci Adv 8(47):eabo3648

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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