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Allele : Il1a<em1Tdk> interleukin 1 alpha; endonuclease-mediated mutation 1, Thirumala-Devi Kanneganti

Primary Identifier  MGI:7431279 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Il1a
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing uses guide RNAs (AAAAGCTTCTGACGTACCACagg and AAGTAACAGCGGAGCGCTTTtgg, PAM sequences indicated by lowercase letters) to delete exons 2 to 6. Il1a transcript from Mus musculus interleukin 1 alpha (Il1a); NCBI Reference Sequence: NM_010554.4, was used as reference for the exon numbering and the guide/donor sequences.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Il1a-KO<line2>,
  • Il1a-KO<line2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories