|  Help  |  About  |  Contact Us

Allele : Nipsnap3b<em1(IMPC)J> nipsnap homolog 3B; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7435701 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nipsnap3b
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGGAGTCTCCGAACAAAGAT and CGTCGCTGTTAAGTACACAG, which resulted in a 10,575 bp deletion beginning at Chromosome 4 position 53,011,600 bp and ending after 53,022,174 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000814213, ENSMUSE00001033419, ENSMUSE00000995530, ENSMUSE00000980454, ENSMUSE00000987062, ENSMUSE00000413885 (exons 1-6) and 9023 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele