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Allele : Tg(ITGAM-cre/ERT2)F9Jckr transgene insertion, Mathias Jucker

Primary Identifier  MGI:7439393 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(ITGAM-cre/ERT2)F9Jckr
Strain of Origin  C57BL/6J × C3H/HeJ Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The transgene consists of the 1,723-bp human CD11b (ITGAM) promoter, a 2,578-bp fragment encoding a rabbit β-globin intron and the CreERT2 sequence, a 603-bp transcript-stabilizing WPRE sequence and a 170-bp spanning SV-40 poly(A) sequence. Three founder lines were generated. information and line numbers were not available. The founder line with the most robust and microglia-specific recombination was chosen for further breeding (F9 line).
  • mutations:
  • Insertion
  • synonyms:
  • CD11b-CreERT2,
  • CD11b-CreERT2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

2 Publication categories