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Allele : Rr381<em4Kap> regulatory region 381; endonuclease-mediated mutation 4, Dietmar J Kappes
Primary Identifier  MGI:7439138 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr381
Is Recombinase  false Is Wild Type  false
molecularNote  The Zbtb7b silencer was targeted with a dsODN template, coding for a version of the silencer sequence where a 40 bp sequence of a highly conserved noncoding element (HCNE; located at the 3' end) containing two conserved Runx binding motifs is moved to the 5' end, using TALEN technology (ZFN target sequences (capitalized) ACCGCTACCCTAACCcataaCTGGAAGGGGTTTAG).
  • mutations:
  • Other
  • synonyms:
  • Sil<ProxRx>,
  • ThPOK<SilProxRx>,
  • Sil<ProxRx>,
  • ThPOK<SilProxRx>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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