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Allele : Rras2<tm1.1Geno> related RAS viral (r-ras) oncogene 2; targeted mutation 1.1, Genoway

Primary Identifier  MGI:7439826 Allele Type  Targeted
Attribute String  Conditional ready Gene  Rras2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing the following elements replaced exon 3: a lox511 site, wild-type exon 3, FRT-flanked neomycin resistance gene, loxP site, exon 3 containing a glutamine to leucine substitution at amino acid 72 (Q72L) in opposite orientation, lox511 site, and loxP site. The neomycin resistance gene was removed via flp-mediated recombination. Upon expression of cre recombinase, the wild-type exon 3 will be removed and the mutated exon harboring the Q72L missense mutation will be inserted in the forward orientation.
  • mutations:
  • Insertion
  • synonyms:
  • Rras2(Q72L)<fl>,
  • Rras2(Q72L)<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories