Primary Identifier | MGI:7439833 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Gcg |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct is designed to insert a rox-flanked STOP cassette (RSR) followed by a creERT2 and an FRT-flanked neomycin resistance (neo) cassette into exon 2 of the gene. Expression of CreERT2 driven by the endogenous Gcg gene promoter occurs only after the removal of RSR by Dre recombinase. |