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Allele : Gt(ROSA)26Sor<tm1(CAG-Bcl2)Zhu> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Yuan Zhang
Primary Identifier  MGI:7446375 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector is constructed based on the Ai6 vector from Addgene with (from 5' to 3') a CAG (CMV enhancer/chicken beta-actin) promoter, an FRT site, a floxed STOP cassette (with stop codons in all 3 reading frames and a triple polyA signal), and murine B cell leukemia/lymphoma 2 (Bcl2) cDNA followed by a woodchuck hepatitis virus post-transcriptional regulatory element (WPRE), a polyA signal, and an attB/attP-flanked PGK-FRT-Neo-polyA cassette. The targeting vector is inserted into the Gt(ROSA)26Sor locus.
  • mutations:
  • Insertion
  • synonyms:
  • R26<LSL-Bcl2>,
  • R26<LSL-Bcl2>
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1 Feature

Trail: Allele

Genome

1 Expresses

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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