| Help | About | Contact Us

Allele : Tg(Vav1-HBEGF,-GFP)1Cfors transgene insertion 1, Camilla Forsberg

Primary Identifier	MGI:7464989	Allele Type	Transgenic
Attribute String	Inserted expressed sequence, Reporter	Gene	Tg(Vav1-HBEGF,-GFP)1Cfors
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

The mouse Vav1 promoter drives expression of a loxP-flanked diptheria toxin receptor (DTR, HBGEF) and stop codon, a second loxP and a GFP gene. GFP is not expressed unless Cre-mediated recombination of the loxP sites occurs.

mutations:
Insertion

synonyms:
Vav-DTR,
Vav-DTR

earliestPublication:
Rodriguez Y Baena A, et al. (2022) New transgenic mouse models enabling pan-hematopoietic or selective hematopoietic stem cell depletion in vivo. Sci Rep 12(1):3156

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76818576

MouseMine