| Primary Identifier | MGI:7486552 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Misp |
| Strain of Origin | FVB/NJcl | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 genome editing technology was used to generate a 5-base deletion (TGCAC) in exon 2 of the gene. This deletion leads to a frame-shift and a premature stop codon (p.S220Qfs*2). Western blot analysis confirmed the absence of protein expression in the colon of homozygous mutant mice. |
