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Allele : Ppp1r12a<tm2.1Nju> protein phosphatase 1, regulatory subunit 12A; targeted mutation 2.1, Model Animal Research Center of Nanjing University
Primary Identifier  MGI:7464861 Allele Type  Targeted
Attribute String  Not Specified Gene  Ppp1r12a
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Threonine codon 852 (ACT) in exon 18 was changed to alanine (GCT) (p.T852A) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 18. The neo cassette was removed through subsequent Cre-mediated recombination. The mutation prevents phosphorylation of the residue.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Mypt1<T852A>,
  • Mypt1<T852A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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