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Allele : Cfap61<em1Yqt> cilia and flagella associated protein 61; endonuclease-mediated mutation 1, Yue-Qiu Tan

Primary Identifier	MGI:7448443	Allele Type	Chemically induced (ENU)
Attribute String	Null/knockout	Gene	Cfap61
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas technology deleted exon 3. RT-qPCR confirmed absence of transcript in homozygotes

mutations:
Intragenic deletion

earliestPublication:
Hu T, et al. (2023) Biallelic CFAP61 variants cause male infertility in humans and mice with severe oligoasthenoteratozoospermia. J Med Genet 60(2):144-153

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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