| Primary Identifier | MGI:7467171 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Arhgap29 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Arginine codon 553 (AGA) in exon 15 was changed to threonine (ACA) (p.R553T c.165G>C) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation is the equivalent of the human p.R551T mutation found in some NSCL/P (non-syndromic cleft lip with or without the palate) patients. |
