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Allele : Zranb1<em1Shios> zinc finger, RAN-binding domain containing 1; endonuclease-mediated mutation 1, Shigeru Oshima
Primary Identifier  MGI:7449310 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Zranb1
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Cysteine codon 443 (TGT) in exon 5 was changed to serine (TCT) (p.C443S) using crRNA (UGAGUCAAGUAAACAAUCUCGUUUUAGAGCUAUGCUGUUUUG), tracrRNA (AAACAGCAUAGCAAGUUAAAAUAAGGCUAGUCCGUUAUCAACUUGAAAAAGUGGCACCGAGUCGGUGCU) and an ssODN template (CGAAGCACCGAGTCTTTGTCATAAATTGCCCCATGTAGCTTGTAGTACTGAGTCAAGTAAAGAATCTCCGGCAGTCCGGTTCCAAAGTGCATATAGTCTACTGTCCAGACGTGTAGCCAACT) with CRISPR/Cas9 technology. The mutation renders the peptide enzymatically inactive.
  • mutations:
  • Single point mutation
  • synonyms:
  • Zranb1<C443S>,
  • Zranb1<C443S>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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