Primary Identifier | MGI:7469461 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(APOL1*E150K)G0altMrpk |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains a human library clone (CTD2333M18) with 100,104 bp clone contained the APOL1 gene about 25 kB of upstream (including exons 1-5 of the APOL2 gene) and about 65 kB of downstream (including exons 4-41 of the MYH9 gene) sequence. The APOL1 sequence includes the amino acids K150, I228, and K255, which is identical to an alternate G0 haplotype. |