Primary Identifier | MGI:7469467 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(APOL1*E150K)G2multiMrpk |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains a human library clone (CTD2333M18) with 100,104 bp clone contained the APOL1 gene about 25 kB of upstream (including exons 1-5 of the APOL2 gene) and about 65 kB of downstream (including exons 4-41 of the MYH9 gene) sequence. The APOL1 sequence includes the amino acids K150, I228, and K255, which is identical to an alternate G0 haplotype. G2multi contains another copy of the transgene with an unknown integration site. |