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Allele : Tg(APOL1*E150K)G2multiMrpk transgene insertion G2multi, Martin R Pollak

Primary Identifier  MGI:7469467 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(APOL1*E150K)G2multiMrpk
Strain of Origin  FVB/NJ Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains a human library clone (CTD2333M18) with 100,104 bp clone contained the APOL1 gene about 25 kB of upstream (including exons 1-5 of the APOL2 gene) and about 65 kB of downstream (including exons 4-41 of the MYH9 gene) sequence. The APOL1 sequence includes the amino acids K150, I228, and K255, which is identical to an alternate G0 haplotype. G2multi contains another copy of the transgene with an unknown integration site.
  • mutations:
  • Insertion
  • synonyms:
  • APOL1<G2multi>,
  • APOL1<G2multi>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories