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Allele : Igh<tm5.1Mbu> immunoglobulin heavy chain complex; targeted mutation 5.1, Meinrad Busslinger

Primary Identifier  MGI:7539580 Allele Type  Targeted
Attribute String  Conditional ready, RMCE-ready Gene  Igh
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  Blastocyts from Ightm4.2Mbu/+ Rosa26CreERT2/+ mice on Gt(ROSA)26Sortm9(cre/ESR1)Arte on a hybrid C57BL/6 × 129/Sv background were used to generate ES cell lines.
molecularNote  CreERT2 activity was induced by 4-hydroxytamoxifen to facilitate Cre-mediated insertion of the PAIR4 sequences into the lox71 site at the deletion point (117,126,667/116,237,220; mm9, Chr.12) of the Ightm4.2Mbu allele. The rox-flanked Actb-Bsd expression cassette was deleted after germline transmission.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Igh<P4-Bsd>,
  • Igh<P4-Bsd>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories