| Primary Identifier | MGI:7488653 | Allele Type | Targeted |
| Attribute String | Inducible, Recombinase | Gene | Aldh1a3 |
| Transmission | Germline | Strain of Origin | 129 x C57BL/6 |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| description | 129B6 hybrid-derived ES cells used. |
| molecularNote | A targeting construct was designed to insert the coding sequence for tamoxifen-inducible Cre recombinase fused with ERT2 and frt-flanked neo selection cassette downstream of the stop sequence of the Aldh3a1 locus with a P2A self-cleaving peptide separating the Aldh3a1 and cre/ERT2 coding sequences. The chimeric female mice were bred with ACTB-Flpe male mice to remove the frt-flanked neo cassette. |
