| Primary Identifier | MGI:7511770 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Mmp14 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Tyrosine codon 573 (TAC) in exon 10 was changed to aspartic acid (GAC) (p.Y573D) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 9. The neo cassette was removed through subsequent Cre-mediate recombination. The mutation changes the residue in the cytoplasmic tail of the encoded peptide from phosphorylatable to a phosphomimetic. |
